coenzyme q10 improves developmental competence of mice pre_antral follicle derived from vitrified ovary

نویسندگان

elmira hosseinzadeh school of biology, damghan university, damghan, iran.

saeed zavareh institute of biological sciences, damghan university, damghan, iran

taghi lashkarboluki institute of biological sciences, damghan university, damghan, iran

چکیده

the aim of this study was to investigate the in vitro developmental competence of isolated pre-antral follicles derived from vitrified ovaries in the presence of coenzyme q 10 (coq 10 ) . mice pre-antral follicles derived from fresh and vitrified-warmed ovarian tissues were in vitro cultured individually in α-mem medium supplemented with or without coq 10 , followed by adding human chorionic gonadotropin (hcg) to induce ovulation. the follicle development parameters and ovulated oocyte maturationwere assessed.the diameter and development of pre-antral follicles and oocyte maturation rates were significantly higher in coq 10 pretreatment groups of both vitrified and fresh samples compared to the respective coq 10 free conditions groups. coq 10 improves the in vitro development of pre-antral follicles derived from fresh and vitrified –warmed ovaries.

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عنوان ژورنال:
journal of paramedical sciences

جلد ۶، شماره ۲، صفحات ۰-۰

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